PUBLICATIONS FROM GROUP MEMBERS

SELECTED RECENT PUBLICATIONS

Diet quality, sleep and quality of life in Parkinson's disease: a cross-sectional study.

Dunk D, Mulryan P, Affonso S, O'Keeffe GW, O'Keeffe M, Sullivan AM. Ir J Med Sci. 2022 Sep 2. doi: 10.1007/s11845-022-03144-1. Online ahead of print. PMID: 36056229

Peripheral administration of the Class-IIa HDAC inhibitor MC1568 partially protects against nigrostriatal neurodegeneration in the striatal 6-OHDA rat model of Parkinson's disease.

Mazzocchi M, Goulding SR, Morales-Prieto N, Foley T, Collins LM, Sullivan AM, O'Keeffe GW.Brain Behav Immun. 2022 May;102:151-160. doi: 10.1016/j.bbi.2022.02.025. PMID: 35217173

Gene Co-expression Analysis of the Human Substantia Nigra Identifies ZNHIT1 as an SNCA Co-expressed Gene that Protects Against α-Synuclein-Induced Impairments in Neurite Growth and Mitochondrial Dysfunction in SH-SY5Y Cells.

McCarthy E, Barron A, Morales-Prieto N, Mazzocchi M, McCarthy CM, Collins LM, Sullivan AM, O'Keeffe GW. Mol Neurobiol. 2022 May;59(5):2745-2757. doi: 10.1007/s12035-022-02768-9. Epub 2022 Feb 17.PMID: 35175558 

Regulator of G-Protein Signalling 4 (RGS4) negatively modulates nociceptin/orphanin FQ opioid receptor signalling: Implication for l-Dopa-induced dyskinesia.

Pisanò CA, Mercatelli D, Mazzocchi M, Brugnoli A, Morella I, Fasano S, Zaveri NT, Brambilla R, O'Keeffe GW, Neubig RR, Morari M. Br J Pharmacol. 2021 Nov 12. doi: 10.1111/bph.15730. PMID: 34767639

LMK235, a small molecule inhibitor of HDAC4/5, protects dopaminergic neurons against neurotoxin- and α-synuclein-induced degeneration in cellular models of Parkinson's disease.

Mazzocchi M, Goulding SR, Wyatt SL, Collins LM, Sullivan AM, O'Keeffe GW. Mol Cell Neurosci. 2021 Sep;115:103642. doi: 10.1016/j.mcn.2021.103642. Epub 2021 Jun 10. PMID: 34119632 

Quinacrine and Niclosamide Promote Neurite Growth in Midbrain Dopaminergic Neurons Through the Canonical BMP-Smad Pathway and Protect Against Neurotoxin and α-Synuclein-Induced Neurodegeneration.

Goulding SR, Lévesque M, Sullivan AM, Collins LM, O'Keeffe GW. Mol Neurobiol. 2021 Jul;58(7):3405-3416. doi: 10.1007/s12035-021-02351-8. Epub 2021 Mar 12. PMID: 33713017